Document Type : Research article
Authors
1
Department of Surgery and Theriogenology, College of Veterinary Medicine, University of Mosul, Nineveh, Iraq.
2
Veterinary Hospital, Agriculture director, Nineveh. Iraq.
3
Department of Surgery and Theriogenology, College of Veterinary Medicine, University of Mosul, Nineveh, Iraq
4
Department of Radiology, College of Medicine, Nineveh University, Nineveh, Iraq.
Abstract
ABSTRACT
This work was designated to reconstruct the experimental bladder defect using acellular bovine pericardium, reinforced with topical application of autogenous plasma-rich fibrin in dogs. A circular defect was induced in the UB of twelve adult stray dogs undergoing a protocol of sedation and anaesthesia. The animals were divided randomly into two groups of 6 each. In the first group, the defect was reconstructed with 4 cm of acellular bovine pericardium (ABP), which was previously prepared. In the second group, cystoplasty was done, and the site of operation was wrapped with previously prepared autogenous platelet-rich fibrin (PRF). Clinical observation was recorded for a few days postoperatively, and radiographic investigation at 7-, 15-, 30-, and 45-days post-surgery was recorded. The radiographic changes in the first group from 7 to 45 days post-surgery showed a distended UB with a consistent pear shape. There were depression irregularities at the upper anterior area of the bladder at the implanted site. No filling defects and no out-bulging in the wall. There was no leakage of urine. In the second group, the radiographic changes at 7, 15, and 30 days indicated that the UB is semi-distended with an altered pear shape and configuration, whereas after 45 days post-treatment, the UB was well-distended with a consistent pear shape, uniform wall, and smooth configuration. No diverticulum nor leakage were recorded. In conclusion, radiographic evaluation showed that using ABP supported with PRF reveals an improvement in the healing process of experimentally induced bladder defects.
Keywords: Acellular pericardium, Plasma rich fibrin, Cystoplasty, Contrast Radiography.
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