CAMPYLOBACTER PHAGES: BIODIVERSITY AND APPLICATIONS

Document Type : Review article

Author

Department of Biology, College of Science, Jazan University, P.O. Box 114, Jazan 45142, Kingdom of Saudi Arabia.

Abstract

Bacteriophages, or phages, are bacterial invading viruses and considered the biosphere's most prevalent biological agents. They reproduce either through a lytic cycle, leading to the lysis of bacterial cells, or a lysogenic cycle by integrating the phage genome into the host genome (temperate phages). Campylobacter (C.) species, particularly C. jejuni and C. coli, are the main cause of “Campylobacteriosis,” a common form of bacterial gastroenteritis worldwide. Campylobacter phages exhibit remarkable biodiversity with significant genetic and morphological variations. Most Campylobacter phages are categorized under the Myoviridae family, while some belong to the Siphoviridae family. Most reported Campylobacter phages infect C. jejuni and C. coli and are lytic phages. This review gives an overview of the biology and classification of Campylobacter phages (lytic and temperate), the application of lytic Campylobacter phages as antibacterial agents to reduce Campylobacter bacteria in the livestock and food industry, and the use of phage typing as a tool for the identification of Campylobacter bacteria.

Keywords

Main Subjects

Files

Share

How to cite

Statistics