BIOCHEMICAL ALTERATIONS IN PREGNANCY TOXEMIC EWES AND TRIALS OF TREATMENT

EL KHDER, GHADA, M.; ISMAIL, EMAN I.M.; DARWISH, MOHAMED E.; MABROUK, MARWA; ABDELRAHMAN, NOHA; MOSTAFA, DOAA I.A.

doi:10.21608/avmj.2024.292913.1269

BIOCHEMICAL ALTERATIONS IN PREGNANCY TOXEMIC EWES AND TRIALS OF TREATMENT

Document Type : Research article

Authors

¹ Chemical, Toxicology, and Nutritional Deficiency Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dooki, Egypt

² Biochemistry Department, Animal Health Research Institute (AHRI)- Zagazig Branch, Agriculture Research Center (ARC), Egypt

³ Clinical Pathology Department, Animal Health Research Institute (AHRI)- Zagazig Branch, Agriculture Research Center (ARC), Egypt

10.21608/avmj.2024.292913.1269

Abstract

The purpose of the current study was to assess the impact of pregnancy toxaemia on hematobiochemical and hormonal changes together with treatment of diseased ewes. This study was done on 15, 3-4 years old (5 healthy-10 ewes suffered from pregnancy toxaemia) were divided into 3 groups (5 /group). Gp (1) clinically healthy ewes (control group), Gp (2) diseased ewes received 150 ml of dextrose (25%) (I/V), 100 ml propylene glycol daily for3 sucessive days (orally), 1ml Cal-De-Mag kgm/ bwt and 1 ampole of vitamin B complex IM, Gp (3) diseased ewes treated with same drug and dose used in 2nd group in addition 0.4 unite insulin/kgm bwt (S/C) daily for 3 sucessive days. Urine samples were collected pre-treatment and post treatment for analyzed for ketone bodies, glucose and protein. Blood was drawn from each subject ewes pre-treatment and at 5 & 10 days post treatment for determination hematobiochemical and hormonal parameters. Pregnancy toxaemic ewes exhibited many signs such as anorexia and depression, disinclin- blindness, inability to move, excessive salivation, teeth grinding, a listening attitude, and sternal recumbency..

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