ON THE PATHOLOGIC EFFECTS OF SOME RODENTICIDES PREPART II THE QUICK ACTING POISONS, CRIMIDINE AND ZINK PHOSPHIDE

Document Type : Research article

Authors

Department of Plant Protection, Faculty of Agriculture, Assiut Uni versity. Department of pathology and Parasitology. Faculty of Medicinessiut University

Abstract

Crimidine caused a relatively rapid death when given in lethal doses. Before death, animals showed neurologic signs suggestive of significant toxic involvement of the central nervous system. Autopsy revealed severe generalized venous congestion most pro bably due to acute heart failure secondary to toxic myocardiosis and tubular necrosis of kidneys probably produced by the concen tration of the poison in renal tubules.
All animals given sublethal dose of Crimidine recovered within few days with the occurrence of minimal histopathologic changes
Zinc phosphide cuased very rapid death of all animals. The post-mortem picture was characterized by severe generalized venous congestion and dilated flabby heart. The most probable cause of death was acute heart failure.