STUDIES ON RESISTANCE OF IRAQI-SHEEP TO DIGTYOCAULUS FILARIA INFECTION

Document Type : Research article

Authors

Dept. of Vet. Medicine and Therapeutics, Faculty of Vet. Med., Baghdad University

Abstract

The resistance of Iraq-sheep to D.filaria was studied on sixteen lambs. Wide variations in degree of resistance were observed. Solid immunity was develop < /strong>ed by two lembs resulted in partial or complete elimination of worm burden of initial infection when challenged 28 days post primary exp < /strong>osure, while other two lambs failed to do so. The resistance was initiated in challenged lambs within seven days after patency of pri mary exposure whereas those Lambs re-infected before patency of initial infection were una ble to evoke any degree of resistance. Immune mechanism in the resistent lexbs app < /strong>e ared to operate in migratory pathway from mesentri lymph nodes to the lungs. The resistent lambs showed resp < /strong>iratory dis tregs similar to those show by non-resistant and control infected animals possibly due to the high susceptibility of this breed to se condary bacterial pneumonia.