SOME STUDIES ON PANCREATIC FUNCTION IN CATTLE AND BUFFALOES 3. ALLOXAN DIABETES

Document Type : Research article

Authors

Depts. of Medicine & Pathology, Faculty of Vet. Med., Assiut University,

Abstract

Diabetes was induced in 5 male cattle by injection of alloxan. Each animal recéived single dose of 5% alloxan solution intravenously. Blood, faecal, urine and duodenal fluid samples were collected before and 1,2,4,7 & 15 days post alloxan injection ( P.A.I. ). Recorded results indicated: 1- Momentary restlessness for about hour where
respiratory and pulse rates increased. The animals returned to normal condition after 16 hrs P.A.I. Ten hours later P.A.I. the animals were fainting
but not commatosed. 2- Polyuria with apparent glucosuria. 3- Increased serum glucose level during the whole
course of experiment. 4- Pancreatic enzymes ( lipase, Amylase & Trypsin )
were not affected. 5- Elevated S-GOT & S-GPT while alkaline and acid
phosphatase enzymes activity was still in the normal level.