MICROSCOPICAL STUDIES OF SMEARS FROM TISSUE AND BLOOD OF BIRDS AFFECTED WITH INFECTIOUS BURSITIS

Document Type : Research article

Authors

Abstract

Changes in bursa, spleen, liver and blood following intraocular ap < /strong>plication of highly patho genic strain of infectious bursal disease, strain Cu-1, were studied in smears from infected Leghorn chicks. These changes consisted of nuclear vacculation, and chromatolysis associa ted with cytoplasmolysis in lymphocytes, macrophages and reticular cells of bursa and spleen, lymphocytes and macrophages in the blood and cytoplasmic vacculation in the epithelial cells of the kidney, while no changes were detected in the liver. It was sugges ted that, by intraocular application the virus may be transmitted to prediliction seats associated with the lymphocytes. Smears from tissues and blood of infected birds seems to be helpful in diagnosis of the disease.