SOME BIOCHEMICAL AND HAEMATOLOGICAL INDICES UNDER THE EFFECT OF PANACUR IN DONKEYS

NAFIE, TH. S.; AMER, A.A.; ABD EL-ALL, TH.S.; KARRAM, M.H.

doi:10.21608/avmj.1986.189912

SOME BIOCHEMICAL AND HAEMATOLOGICAL INDICES UNDER THE EFFECT OF PANACUR IN DONKEYS

Document Type : Research article

Authors

10.21608/avmj.1986.189912

Abstract

Agroup of 16 Donkeys aged 3.5-4.5 years were proved to be heavily infested with Trichostrogylidae (1971. 9 + 1297.2 Egg/gm faeces). Evaluation of some biochemical and haematolo gical parameters was carried out before and after treatment by Panacur* as an anthelmintic. The used dose was 5 mg Fenbendazole (Panacur) /1 kg B.W. orally for one time, The biochemical picture recorded highly significant elevation in serum glucose and in total protein levels 5 and 10 days after treatment.
A temporal significant oligocythaemia was evident 5 days post treatment that returned to the normal levels 10 days post treatment. There was a marked improvement in the haemoglobin levels 15 days post treatment. A highly significant increase was recorded in the Mean Corpuscular Volume (M.C.V) while a highly significant leucopenia, lowered immature reticulocytes with highly significant Neutrophilia and Monocytosis. Panacur** has proved to be a highly effective anthelmintic for donkeys as the total egg count/gm faeces has been dropped sharply after dosing. All donkeys proved to be free from the parasitic infestation 5 days after treatment and no parasitic eggs detec ted in their faeces.