IN VITRO LYMPHOCYTE PROLIFERATION RESPONSES OF BOVINE NEONATES DELIVERED FROM DAMS VACCINATED WITH BCG AND OF CALVES DELIVERED FROM VACCINATED DAMS AFTER INOCULATION WITH BCG AT BIRTH

Document Type : Research article

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Abstract

Eight pregnant cows at 6 months gestation period were inocula ted intradermally with BCG vaccine. The animals gave detectable cell-mediated immune response as determined by the in vivo skin test and the in vitro lymphocyte proliferation assays. Proliferative responses of cells from calves delivered from BCG vaccinated dams and calves from non vaccinated dams and vaccinated with BCG postpartum, were eliezed by PPD stimulation, while mitogen responsiveness to Concanavaline A was demonstrated in the calves from BCG vaccinated dams only.