PRELIMINARY STUDIES ON THE EXOPRODUCTS OF PSEUDOMONAS AERUGINOSA

Document Type : Research article

Authors

Abstract

Study was carried out on the expoproducts of 15 strains of Ps.aeruginosa isolated from wound infection, otitis media and urinary tract infection. It was noticed that the exoproducts exhibited lethal effect when injected intraperitonealy into white mice as well as dermonecrotic activity when injected into skin of rabbits. As regards the haemolysin activity, it was detected for all the products by agar well technique and the tube method. Also, the exoproducts had antimicrobial activity on Gram-positive and some Gram-negative organisms. All these activities were thermolabile at 60°C for 10 minutes.