RED BLOOD CELL PICTURE AND TOTAL LEUCOCYTIC COUNT IN ALBINO MICE INTOXICATED WITH ALLIUM SATIVUM L.

Document Type : Research article

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Abstract

Haemogram findings during garlic toxicity were studied on 300 albino mice (20-53 gm). The mice were given daily 1/10 LD so of crude hexane extract and its three fractions (A,B,C) for 8 weeks. haematological results revealed a marked decrease in the total R.B.Cs, Hb concentration, PCV and MCHC, while there was a highly significant elevation in the MCV which indicates a case of macorocytic hypochromic anaemia. Also Heinz bodies were demonstrated in stained blood films of toxicated mice. Leucocytosis was evident along the period of the experiment.
Assiut Veterinary Medical Journal
Volume 22.2, Issue 44
January 1990
Pages 145-154

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