SPERMATOGENIC PROCESS IN CARBENDAZIMTREATED RATS

Document Type : Research article

Author

Abstract

Six groups of adult male albino rats (3 animals each) were employed in this study. The 1st griyo (control) was given 2 ml corn oil/rat. From the fungicide Carbendazim; 200, 100, 50, 25 and 10 mg/Kg, emulsified in corn oil. A single dose of Carbendazim produced both dose- and stage- related changes, especially at certain stages (VII, XII-XIII & XIV) of the seminiferous epithelium. These changes were represented as multinucleated giant round spermatids, and premature release (sloughing) of the elongated spermatids. The least effective dose (25 mg/kg), caused sloughing of elongated sp < /strong>ermatids only at stage VII. Meanwhile, at dose 200 and 100 mg, the sloughing app < /strong>eared at about 50% of stage VII and extended to be 100% of stages XII-XIII & XIV.