FERTILITY IN RAMS TREATED WITH CLOMIPHENE CITRATE

The effect of orally administered clomiphene citrate on the fertility of rams was studied. Semen and blood samples were collected from a five mature and fertile Rahmani rams (control) twice per week for 3 weeks. Each ram was treated with 100mg-clomiphene citrate for 5 days. Semen
the clomiphene citrate and blood samples were collected again from treated rams (CC treated) for the same period. Semen parameters (sperm motility, live sperm, and sperm concentration) were assessed in the two groups. Blood samples were subjected to radioimmunoassay for
assessment of testosterone concentration in the control and CC treated rams. A reduction in the values of semen parameters was observed in the CC treated rams. Testosterone concentration was significantly decreased (approximately 50% from control rams) by clomiphene citrate treatment. It could be concluded that clomiphene citrate has a deteriorative effect on semen quality and testosterone concentration when it is orally administered to mature and fertile rams.