STUDIES ON EXPERIMENTAL INFECTION WITH CANINE PARVO VIRUS IN FREE-RANGING RED FOXES (VULPES VULPES)

Document Type : Research article

Authors

1 Dept. of Pathology, Fac. Vet. Med., Suez Canal Univ.

2 Dept. of Wildlife, Fac. Vet. Med., Suez Canal Univ., Ismailia

3 Animals Veterinary Serum and Vaccine Research Institute, Abassia

Abstract

The virulent strain of CPV at the 3 rd tissue culture passage on Norden laboratory feline kidney cell (NLFK) was tested Experimentally in 12 clinically healthy wild caught free-ranging red foxes (Vulpes Vulpes) from Sinai desert and inoculated oro-nasally with the virulent strain. The inoculated were shown clinical symptoms of parvo virus. The clinical symptoms of canine parvo virus disease which were fever, vomiting, diarrhoea with foul smelling and tangled with blood, anorexia, and obvious rapid dehydration. At necropsy, the heart showed whitish streaks on the surface of the ventricles. The intestine had catarrhal exudate and the mesenteric lymph nodes were enlarged and oedematous. Multifocal grayish areas were seen on the liver surface. Microscopically, there was chronic local extensive myocarditis with infiltration of giant cells. Fibrosis was also seen in the myocardium. Necrotic enteritis was noticed and lymphoid depletion was seen in the spleen. The liver had focal lymphocytic hepatitis. Serological tests were carried out to detect canine parvo virus from infected tissues and to determine the serum antibody titres in infected foxes.

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