ESTIMATION OF ANTIBIOTICS, SULPHONAMIDES AND NITROFURANS RESIDUES IN CHICKEN MEAT

Fourty chicken muscle, ten liver and ten kidney samples were collected randomly from Assiut Governorate and analyzed for antibiotic, sulphonamide and nitrofuran residues. Chloramphenicol (CAP) residues were measured by enzyme immunoassays (ELISA) and confirmed with radioimmunoassay (RIA). CAP was found in 40, 30 and 30% of the analyzed muscle, liver and kidney samples with mean values of 6.443 + 5.963, 2.015 1.573 and 4.002 +4.610 ppb, respectively. One muscle and kidney sample were contained violative amounts of CAP residue (20.5 and 10.5 ppb, respectively) and exceeded the Maximum Residue Limit (MRL = 10 ppb) allocated by European Economic Community (EEC). Streptomycin, Dihydrostreptomycin, Gentamycin, Spectinomycin, Oxytetracyclin (OTC), Erythromycin, Lincomycin, Trimethoprim, Ampicillin, Oxacillin, Benzylpenicillin (Penicillin G) and Phenoximethyl-penicillin (penicillin V) residues that screened by using electrophoretic technique could not be detected in all investigated samples. Neither sulphonamides nor nitrofurans were detected by HPLC-DAD in all analyzed samples. Health hazards of the investigated drugs were discussed.