Effect of nigella sativa and trigonella greacum on reducing the withdrawal of trichlorfon in chicken

Authors

1 Animal Health Research Laboratory, Beni Seuf

2 Animal Health Research Institute Dokki

Abstract

The effect of fenugreek Trigonella feonum and Nigella sativa seeds on
special regard to residues as well as toxicity with trichlorfon clinicopathological changes in chickens were investigated. 35 chickens were used in this study. They were divided into two groups, control group (6) and experimental group (EG) 29.EG received ration contains
tricholrfon 0.15% for 4 successive weeks. 5 birds were slaughtered and the rest was subdivided into 4 equal groups of birds. Group A treated with 4% trigonella feonum TF, group B treated with 1.5% nigella sativa NS, group C treated with a mixture of TF and NS and group D not treated for further 4 weeks Results showed decreased level of RBCs,PCV,HB, WBCs, total proteins and increased values of creatinine BUN, AST and ALT activities in trichlorfon treated group, with pathological changes in liver, spleen, kidney and intestine. While group treated with TF, NS each alone showed improvement result than the combined group. Residues analysis showed that TF and NS each alone accelerated depletion of trichlorfon residues in, liver, kidney and muscles more than the combined group. On conclusion the combination of TF and NS may antagonize each other and delay the improvement of regeneration cells of kidney, liver and spleen. The use of TF and NS each alone had beneficial effect against trichlorfon toxicity, pathological and clinicopathological effects and complications were recorded.

Keywords

Assiut Veterinary Medical Journal
Volume 54, Issue 116
January 2008
Pages 285-301

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